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You selected inventions in category Biology

  • Intelligent Dental Surgical RobotIntelligent Dental Surgical Robot
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      AIM OF THE PROJECT►►
      Dentistry is the branch of medicine that requires a lot of power for a dentist. To enhance the quality of dental services and avoid all the problems mentioned and For ease of operation such as (Anesthetic infusion, X-RAY Photography, Time Management and milling tooth and …) we have decided to design this robot to earn these benefits:
      1- Avoid touch the Dental ando system to lips and tongue
      2- Tooth milling operations by robot
      3- Dental radiography by robot
      4- Video record via robot system in 5MP resolution
      5- Anesthetic infusion To the target by robot

      6- Time management
      7- Reduce of the extra costs
      8- to avoid being exposed to infectious agents such as practitioners (HCV, HBV «hepatitis B, C», and bacterial and fungal infections)
      9- Prevention of Musculoskeletal Disorders as "back pain, wrist pain, headaches, shoulder pain, back pain, neck pain"
      10- Avoid visual fatigue and premature fatigue.
      11- Avoid exposure to noise pollution
      12- Abatement of exposure to the rays' ionizing or non-ionizing "
      13- prevent skin allergy, allergy
      14- avoid the risks and hazards of chemicals such as mercury dental amalgams, resins, sealers and ...
      15- Dental decay Detection intelligent devices via the piezoelectric system with 100% accuracy without any complications
      16- In deprived regions by a dentist From anywhere in the world Controlled of the Internet (Including the poor and disadvantaged countries that Not respected The oral health ،Peoples can Repair the Teeth)
      ►► GENERAL INFORMATION  Radiographic imaging (X-RAY) by robots 150DPI
       Film record via robot camera with (800*600) resolution
       Anesthetic injected into the mouth Target with adjusted 0.02mm
       Tooth operations intelligent robot with adjusted 0.02 mm

       Prevent wasted time (the robot operating time reduces to 15% )
       Prevent exposure to infectious agents such as (HCV, HBV «hepatitis B, C», and bacterial and fungal infections), 90% of patients will reduce.
       Prevent musculoskeletal disorders in dentists' pain, ankle pain, headaches, shoulder pain, back pain, neck pain, " 100% prevent this disease ".
       Prevent vision fatigue and premature fatigue ,100% prevent this disease.
       Avoid exposure to noise by up to 70% reduced.
       Prevent exposure to radiation as "ionizing and non-ionizing " 100% prevent this disease"
       Prevent skin irritation, allergies and the risk of AIDS and hepatitis, with this method, 100% of those diseases can be prevented.
       Abatement of hazards, chemical hazards, such as dental mercury amalgam, resins, sealers, etc. With this method, 70% of these illnesses can be prevented.
       Prevent physician fatigue and adverse events with up to 100% of this procedure is to prevent these diseases.
       The remote control system via Internet.
       Dental decay Detection Portable intelligent devices via The piezoelectric system with 100% accuracy without any complications

      ►►Used Technologies: Buhler Stepper motor ▬ DV camera for image process ▬ computer brain interface control system majol ▬ 7" tablet for controlling system ▬ six degree joystick- Atmega256 microcontroller etc. ▬ ABS parts for Robot assembly ▬ Brushles motors ▬ 50 M ultrasonic Sensors ▬ plaxyglass elements ▬ micro cam via 50 DPI resolution ▬ LCD monitor5" ▬ SONCEB OZ stepper motor
      ►►Working Principle: Robot electrical system Is provided By a 24 volt 12 amp power adapter that is connected to AC power. Robot performance is explained briefly below:
      1- This robot that connected to the dental unit We Help into the patient's mouth
      2- Robots are fixed in the patient's mouth
      3- Via stepper motors controller and rotational base motor ,In terms of mechanism, imaging needed and video recorder and Anesthetic infusion ,teeth milling tools, selected location desired Dentist ,Is regulated by the dentist. 4- As needed by selecting any of the items and press the button to start the robot works
      5- When we got to the final stage of tooth ra

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    • DNA APTAMER RECOGNIZING ARGININE TAG APPLICATION IN BIOTECHNOLOGYDNA APTAMER RECOGNIZING ARGININE TAG APPLICATION...
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        The development of modern molecular biology, biotechnology and medicine is dependent on availability of high-quality protein products. They are often produced in prokaryotic or eukaryotic expression systems. Recombinant proteins are usually fused with a short oligopeptide tag to provide fast and easy purification procedure based on the affinity chromatography technique.
        The offer is a DNA aptamer that recognizes Arg-Tag.

        DNA aptamers are single-stranded short DNA oligonucleotides characterized by high specificity and affinity to target molecule. In the present invention molecular target can be any molecule: peptide, protein or DNA derivative containing Arg-Tag.
        DNA aptamer that recognizes Arg-Tag – application in:
         Purification of the target molecules containing an Arg-Tag.

        The offered Anti-Arginine Tag DNA aptamer for biotechnological applications is patent pending. Further research and development of the invention are continued at the Faculty of Biochemistry, Biophysics and Biotechnology of the Jagiellonian University. Currently the Centre for Innovation, Technology Transfer and University Development (CITTRU) is looking for entities interested
        in commercial application of the invention.

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      • ANTI-HISTIDINE TAG DNA APTAMERS FOR BIOTECHNOLOGICAL APPLICATIONSANTI-HISTIDINE TAG DNA APTAMERS FOR...
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          Prokaryotic and eukaryotic expression systems for the production of recombinant proteins are used on a large scale in scientific research. The genetically engineered fusion tags, e.g. histidine tag (His-Tag) are used for fast and efficient purification
          of the desired recombinant proteins. The high affinity of His-Tag to the certain metal ions (cobalt, copper, nickel or zinc) enables the application
          of chromatographic media with the above mentioned ions for the purification
          or immobilization of His-Tagged proteins.

          His-Tag recombinant protein can be detected in western blotting using anti-His mono- and polyclonal antibodies. Short His-Tag can be used to investigate protein-protein interactions in techniques such as pull down assays, immunoprecpitation, co-immunoprecipitation or Far-Western blot analysis.

          DNA aptamers are single-stranded DNA oligonucleotides of approximately 4-100 nucleotides that exhibit a high affinity and specificity to their corresponding ligand. An optimal binding between target molecule and selected aptamer is possible due to the rich secondary and tertiary structures of the latter one.

          The subject of the offer are unique sequences of single-stranded DNA aptamers that recognize His-Tag and their application in biotechnology in analysis of His-Tagged molecules (peptides, proteins or DNA derivatives).


          The offered DNA aptamers can be used for analysis of molecules containing a His-Tag, and in particular to:
          • application as a agonist for anti-histidine antibodies;
          • purification and detection of the target molecules containing a His-Tag.

          In addition to the above applications, DNA aptamers can be used as molecules
          with attached tags, especially fluorescent, and in particular to label the molecular targets containing His-Tag. This type of molecules can be successfully used e.g. to study the interaction between proteins using spectroscopic techniques.


          The offered Anti-Histidine Tag DNA aptamers for biotechnological applications
          is patent pending. Further research and development of the invention are continued at the Faculty of Biochemistry, Biophysics and Biotechnology of the Jagiellonian University. Currently the Centre for Innovation, Technology Transfer and University Development (CITTRU) is looking for entities interested
          in commercial application of the invention.

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        • The subject of the offer is a group of mixed dopamine and serotonin modulatorsThe subject of the offer is a group of mixed...
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            Key facts:
            - Lead structures classified as multimodal agents (serotonin, dopamine receptors ligands)
            - Lead structures display anti-psychotic, pro-cognitive and pro-social efficacy; the latter suggesting favorable effects on negative symptoms of psychoses
            - Uncomplicated synthesis
            In vitro testing:
            - Compounds display high affinity for dopaminergic D2 and D3 receptors and serotoninergic 5-HT1A, 5-HT2A, 5-HT6, 5-HT7 receptors; they were mostly classified as D2, 5-HT2A antagonists
            - Compounds have no affinity for M1, H1 lowering the risk of side effects related to cholinergic-, histaminergic- activity
            - Lead structures are brain penetrant
            - Lead structures display acceptable CYP interaction, no toxicity (hERG)
            In vivo testing:
            - Favorable profile in tests predictive of anti-psychotic activity: PCP-induced hyperactivity, conditioned avoidance response (CAR), prepulse inhibition (PPI), social interaction
            - Pro-cognitive efficacy in the novel object recognition (NOR) test, attentional set shifting (ASST), and others suggesting an enhancement of prefrontal flexibility disturbed in schizophrenia
            - Activity was confirmed following oral administration
            - Lead structures don’t affect ECG in guinea pigs and show lack of cardiovascular effects in rats, suggesting the lack of cardio-toxicity

            Compounds may be regarded as drug candidates for the treatment of schizophrenia symptoms and cognitive impairment.

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          • Manual ExoskeletonManual Exoskeleton
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              An exo skeleton device design to aid the mobility of the crippled, The user of this device can with its aid, walk, sit and stand and even climb stairs .It consists of a flat rod at the back replicating the spinal column also designed to be comfortable when the user is sitting down, it has adjacent flat rod at the back of the shoulders, this contains the controls, minor, normal movement of the upper body parts should trigger movement in the limbs. It also consists a box at the lower back or waist region which contains the system transmiting the control and movement to the lower parts of the body. The device can be dissembled into three parts name the back and the two limbs for easy parking. The entire design is completely manual, no batteries, sensors or robotic parts or charging needed. Design will walking seem natural for the user and is qiute skeletal and simple, could be concealed under some clothing.

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            • hair regrowth therapy for bald head personshair regrowth therapy for bald head persons
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                I have a successful research on hair regrowth therapy for bald head person by using my hair oil. I want to suggest for selling my formula or otherwise i want to have a partners for selling my products. The major merits of my research there has side-effects at all for bald head gents only. Hereafter i also have make to prevent the hair loss for both sex. Kindly contact my address, J.Parthasarathi,S/o,A.Jawahar, 812,Mundagan St., Sivakasi - 626123. My Contact # is 9443547064.
                With thanks & regards
                J.Parthasarathi,B.Sc.,PGDMLT.

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              • Application of angiotensin1-9 for dendritic cells stimulationApplication of angiotensin1-9 for dendritic cells...
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                  The subject of the offer is an application of a biogenic peptide to stimulate chemotaxis of dentritic cells, and thereby to modulate the immune response. The increase in migration capacity of these cells of clinical relevance and may be useful in treatment of autoimmune diseases, viral infections and atherosclerosis, as well as during preparation of cancer vaccines ex vivo.

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                • New application of dextran derivatives for anemia treatmentNew application of dextran derivatives for anemia...
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                    The subject of the offer is the application of modified dextran derivatives to prevent or treat anemia of various etiology. Offered solution is characterized by favorable safety profile, and thus may be used to treat patients with contraindications to treatment with other anti-anemia drugs.

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