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You selected inventions in category Biology

  • New sources of energyNew sources of energy
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      Description

      new energy sources.
      Use gravity (gravity), geothermal effect (warm ground), solar energy, power flows of rivers, the wind.
      Maximum security.
      For the staff, (for maintenance), environment (ecology), for the state (strategic security).
      High efficiency. High power (from 1KVt to 1000 MVt and more). Universal application.
      The minimum cost price of electricity.

      1 - power converter steam (air), low pressure. Patent RF 2215183.
      When small amounts has enormous potential power. No competition. Able to replace nuclear
      power, hydropower, thermal power plants.

      2 - inverter air flow (of water). Patent RF 2219369.
      more efficient than traditional turbines. When used in water can replace the hydroelectric power station.

      3 - know-how. Super battery. The new principle of accumulation of electricity.
      Able to replace hundreds of conventional batteries

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    • Detection of causative agents of ocular and nervous system infectionsDetection of causative agents of ocular and...
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        The present technology is related to diagnosis method for detection of single or more causative agents of ocular and nervous system infections among many probable pathogens. The invention provides a rapid assay for the simultaneous detection of the pathogens responsible for infections of the eye and central nervous system for which immunological parameters are not indicative of an active infection but only indicative of exposure to the pathogen and for which classical microbiological assays such as bacterial and fungal cultures are neither sensitive enough to detect the pathogen nor rapid enough to identify the pathogen within 48 hours. In addition aqueous humor or vitreous fluid in case of endophthalmitis will be sufficient in order to detect and discriminate the infectious agent. This obviates the necessity of surgical procedure such as vitrectomy to be performed in an operating room.

        This technology combines the high sensitivity of PCR assay and the high specificity of identification by hybridization on to a macro-array with the detection of hybridization by color detection methods, the end result of which can be monitored by naked eye.

        The invention features a multiplex assay for the simultaneous detection and discrimination of pathogens that cause infections of the eye and CNS comprising:

        1) Processing the clinical samples such as corneal scraping or conjunctival swab or aqueous humor or vitreous fluid or vitrectomy lavage collected or cerebrospinal fluid aspirate or pus collected from brain abscess material or an epiretinal membrane from a patient suspected of being afflicted with eye or a CNS infection, to isolate DNA by standard methods.
        2) Amplifying a specific region of DNA from a gene that is specific to each of the pathogens by a single tube PCR technique using labeled amplification primers for each of the pathogens known to cause CNS and eye infections
        3) Detection and discrimination of pathogens using a DNA hybridization wherein the immobilized target sequences specific for each of the pathogens are reacted with amplified DNA probes generated from the PCR reaction and monitoring the hybridization by color development using specific set of reagents.

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      • Nanoparticle for drug deliveryNanoparticle for drug delivery
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          The technology suggests a sustained-release nanoparticle composition composed of a copolymer of an N-alkylacrylamide, a vinyl monomer, and a polyethylene glycol conjugate for preventing or treating a disease or a condition. The said nanoparticle composition further contains a therapeutic agent such as an antibiotic, anti-restenotic agent, anti-proliferative agent, anti-neoplastic, chemotherapeutic agent, cardiovascular agent, anti-inflammatory agent, immunosuppressive agent, or anti-tissue damage agent. Such nanoparticle compositions generally have a diameter in the range of 20 nm to 100 nm and are used locally for the prevention or treatment of diseases or conditions.
          The said technology also suggests a method for using a sustained-release nanoparticle composition for preventing or treating a disease or condition. The preclinical studies of this technology have been performed on animal model (rat).

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        • Process of Preparation of nanoparticles for drug delivery systemProcess of Preparation of nanoparticles for drug...
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            The present invention is related to a process for the preparation of the novel nanoparticles of apotransferrin / transferrin which are useful for the preparation of a pharmaceutical composition facilitating easy delivery of the drug.
            What is Novelty
            • Prior methods uses the cross linking of apotransferrin with the bioactive compound where cross linking reduce drug efficacy and removal of cross linking is rate limiting. While in present invention apotransferrin has not cross linked with bioactive material and hence the release of bioactive material may not be rate limiting and become instantaneous and release into the cell.
            • Present invention provides a non-toxic delivery system.

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          • Detection kit for Sexually transmitted diseasesDetection kit for Sexually transmitted diseases
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              The present technology provides a multiplex PCR based prototype kit for detection of the Chlamydia trachomatis and Neisseria gonorrhoeae, based on designed primers. The kit contains all the reagents for collection of clinical samples, for carrying out amplification by PCR and the detection of the product, as well as the protocol to be used for diagnosis of Chlamydia trachomatis and Neisseria gonorrhoeae in patient samples. The kit also provides a new transport medium that is not only suitable for collecting the sample but also storing the sample at 4°C for several days. An internal control has also been designed against human gene to test for any PCR inhibition in the sample.

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            • Herbal remedy to prevent atherosclerosisHerbal remedy to prevent atherosclerosis
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                This technology suggests an herbal preparation for prevention of atherosclerosis and hyperlipidemia. The said preparation is anti-inflammatory anti oxidant and increases serum HDL and more specifically it inhibits Lox-15, cox-2 and Ca deposition in the plaque, increases collagen in the chronic plaque, increases serum HDL and decreases serum TG. This herbal preparation contains mixer of Commiphora mukul, Bosewellia, Semecarpus anacardium, Strychnos nux vomica, Terminalia arjuna, Shankha, Rubia cordifolia, Bacopa monnieri, Triphala and Trikatu. Male rabbits have been used for preclinical studies.
                What is Novelty?
                • There is no single medicine which can prevent atherosclerosis and hyperlipidemia
                • To manage this disease patient has to take several medicines, which leads to psychological depression while present technology in the form of single tablet to cure atherosclerosis and hyperlipidemia
                • This medicine does not have any side effects

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              • Process of preparation of diabetic remedyProcess of preparation of diabetic remedy
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                  Present technology is related to a process for extracting an herbal product for prevention of diabetic nephropathy, radiation hazards and age related chronic diseases. The objective of present technology is to develop a herbal product, which could be helpful in preventing diabetic nephropathy and other pathologies, related to over activation of PKC pathway such as DNA break due to radiation and chemotherapy, apoptosis of beta cells, early aging, over expression of inflammatory genes.

                  What is Novelty
                  • Novel plant extract is used for treatment of diabetics and its mechanism of action was also not known.

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                • Production of melanin from fungusProduction of melanin from fungus
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                    This technology is related to process of production of melanin. According to this technology melanin can be easily produced by growing fungus in culture medium.The fungus used in technology is natural and wild type organism. The melanin is secreted externally into the culture medium and is harvested from there. It is a natural melanin and not synthetic.
                    What is Novelty
                    • Earlier melanin production technologies uses genetically modified organism whereas this technology uses natural organism.
                    • Melanin produced from earlier technologies is synthetic and expensive while melanin obtained from present technology is natural and inexpensive.

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